Fixed tissue medical devices comprising albumin-binding dyes
US5509932A · kind A · utility
46Cited by
19References
32Claims
0Family size
Inventors
Key dates
| Filing date | Apr 8, 1993 |
| Grant date | Apr 23, 1996 |
| Priority date | — |
| Expiry date | Apr 8, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2/2412
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An implantable medical device is provided which comprises a fixed tissue incorporating an amount of an albumin-binding dye effective to form a coating of endogenous albumin on said device when the device is in contact with a physiological fluid containing albumin. These albumin-binding dyes have been found to significantly reduce calcification when incorporated in tissue heart valves. A method of increasing the albumin-binding ability of an implantable medical device is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.