Patent · US Expired

Method of screening a peptide library

US5510240A · kind A · utility

101Cited by
20References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 8, 1993
Grant dateApr 23, 1996
Priority date
Expiry dateFeb 8, 2013

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/817
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The instant invention provides a library of bio-oligomers of defined size and known composition, in which the library contains all of the possible sequences of the bio-oligomers, and a method of synthesis thereof. The bio-oligomers of the library may be peptides, nucleic acids, or a combination of the foregoing. The instant invention also provides methods to identify bio-oligomers from a library that demonstrate desired characteristics such as binding, bioactivity and catalytic activity. Thus the instant invention provides a unique and powerful method to identify a useful bio-oligomer sequences from a library more quickly than current state-of-the-art technology allows. Effector molecules for use in treatment or diagnosis of disease are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.