Method of controlling the degradation of glycoprotein oligosaccharides produced by cultured Chinese hamster ovary cells
US5510261A · kind A · utility
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13Claims
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Key dates
| Filing date | Jan 12, 1995 |
| Grant date | Apr 23, 1996 |
| Priority date | — |
| Expiry date | Jan 12, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y302/01018
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A neuraminidase enzyme with unusually high activity under extracellular culture conditions has been discovered in Chinese hamster ovary (CHO) cells and other types of cells. By affecting the neuraminidase activity of the cell culture, the degradation of glycoprotein oligosaccharides produced by these cultured cells can be controlled.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.