Antihypercholesterolemic compounds and related pharmaceutical compositions and methods of use
US5510340A · kind A · utility
1Cited by
5References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 12, 1992 |
| Grant date | Apr 23, 1996 |
| Priority date | — |
| Expiry date | Jun 12, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J71/0042
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel antihypercholesterolemic agents are provided. An exemplary group of compounds has the structural formula (I) ##STR1## wherein R is a C-17 side chain, R.sup.1 is --OH, .dbd.O, or the like, and X and Y are N, N.fwdarw.O, CH, C--OH, C--OCH.sub.3 or C--Z. Methods of using the compound of formula (I) or other novel oxysterol analogs to treat hypercholesterolemia are provided, as are pharmaceutical compositions containing the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.