Patent · US Expired

Di-tert-butylphenol compounds with heterocyclic moiety, useful as anti-inflammatory agents

US5510361A · kind A · utility

10Cited by
10References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 20, 1994
Grant dateApr 23, 1996
Priority date
Expiry dateOct 20, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D261/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The subject invention relates to compounds having the structure: ##STR1## wherein a) each R is independently alkyl having from 1 to about 7 carbon atoms; PA1 b) Z is O or N--X; PA1 c) X is selected from hydrogen, alkyl having from 1 to about 7 carbon atoms, C(O)Y, C(S)Y, and SO.sub.2 Y; PA1 d) Y is selected from R', OR' and NR'.sub.2 ; and PA1 e) R' is selected from hydrogen, alkyl having from 1 to about 7 carbon atoms, and phenyl. The subject invention also relates to pharmaceutical compositions comprising the above compounds, and methods of treating inflammation or pain using the compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.