IL-1.beta.protein precursor
US5510462A · kind A · utility
26Cited by
1References
1Claims
0Family size
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Key dates
| Filing date | Apr 25, 1988 |
| Grant date | Apr 23, 1996 |
| Priority date | — |
| Expiry date | Apr 25, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/141
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention concerns a nucleic acid comprising a nucleotide sequence encoding human interleukin-1 (IL-1), and fragments thereof, and the polypeptides and peptides obtained. Specifically, the subject invention comprises the cloning of a cDNA synthesized by reverse transcription of poly(A)RNA isolated from adherent human monocytes-stimulated with bacterial endotoxin. Human IL-1 is useful to induce the production of IL-2 by activated T-cells; it also acts on B-cells and NK-cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.