Method of preparing 1-amino-2, 6-dimethylpiperidine

US5510489A · kind A · utility

Assignee

• Cassella Aktiengesellschaft · DE

Inventors

• Wolfgang Rybczynski · Bad Camberg, DE
• Wolfgang Bauer · Krefeld, DE
• Eckard Kujath · Maintal, DE
• Manfred Schrod · Weiterstadt, DE

Key dates

• Filing date: May 17, 1994
• Grant date: Apr 23, 1996
• Expiry date: May 17, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/30
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to improved processes for the preparation of 1-amino-2,6-dimethylpiperidine whereby the yield is more than 90%. The processes involve the hydrogenation of 1-nitroso-2,6-dimethylpiperidine in the presence of a palladium catalyst which is partly poisoned with iron ions, in an aqueous solvent, and are characterized by the inclusion of at least one surfactant. The surfactant preferably is anionic or nonionic.