Patent · US Expired

Glucagon-like insulinotropic peptide analogs, compositions, and methods of use

US5512549A · kind A · utility

233Cited by
3References
28Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 18, 1994
Grant dateApr 30, 1996
Priority date
Expiry dateOct 18, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S977/915
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Glucagon-like insulinotropic peptide (GLP-1(7-37)) analogs and derivatives are disclosed. The analogs include amino acid substitutions, amino and carboxyl terminal modifications, and C.sub.6 -C.sub.10 acylations. The claimed compounds stimulate the secretion or biosynthesis of insulin in poorly functioning beta cells and are therefore useful in treating Type II diabetics

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.