Methods for preparing porphyrin-like compounds

US5512675A · kind A · utility

Assignee

• University of British Columbia · CA

Inventors

• Hang Tang · Vancouver, CA
• Lily Xie · Vancouver, CA
• Tilak Wijesekera · Glen Mills, US
• David Dolphin · Vancouver, CA

Key dates

• Filing date: Jun 15, 1993
• Grant date: Apr 30, 1996
• Expiry date: Jun 15, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B59/004
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for synthesizing a porphocyanine having the formula: ##STR1## where each R is ethyl, comprises either: (1) treating 3,3'-4,4'-tetraethyl-5,5'-bisaminomethyl-2,2'-dipyrromethane with a 10-fold excess of DDQ or PA1 (2) treating 3,3'-4,4'-tetraethyl-5,5'-diformyl 2,2'-dipyrromethane with ammonia, followed by column chromatography purification and evaporating to dryness the eluant containing the purified product.