Immunologically active conjugates and method for their preparation

US5514559A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Christine Markert-Hahn · Penzberg, DE
• Beatus Ofenloch-Haehnle · Wielenbach, DE
• Eva Hoess · Starnberg, DE
• Erasmus Huber · Garching bei München, DE

Key dates

• Filing date: Mar 29, 1994
• Grant date: May 7, 1996
• Expiry date: Mar 29, 2014

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/811
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Novel conjugate of the general formula EQU A--L.sub.1 --L.sub.2 --B wherein A and B are the substances to be coupled selected from the groups of haptens, proteins, polysaccharides, soluble polystyrenes, or peptides, L.sub.1 and L.sub.2 are trivalent linkers and L.sub.1 and L.sub.2 are bound via two thioether. They can be used in immunological assays and exhibit an improved storage stability.