Method and composition for testing blood for hemoglobin S that incorporates mineral oil as an insoluble upper phase
US5514592A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 13, 1995 |
| Grant date | May 7, 1996 |
| Priority date | — |
| Expiry date | Feb 13, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for testing blood for the presence of hemoglobin S wherein a blood sample is vigorously admixed with a two-phase test system for the purpose of determining the presence or absence of hemoglobin S after separation of the phases and wherein the two-phase test system involves an aqueous phase containing a lysing agent, a chemical reducing system and a phosphate ion buffer system; and an immiscible phase of mineral oil. The hemoglobin S presence is determinable by the color of a band formed at the interface of the aqueous and immiscible phases and wherein the invention further includes a composition suitable for testing whole blood for hemoglobin S.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.