Patent · US Expired

Method for treating and inhibiting gastric and duodenal ulcers

US5514660A · kind A · utility

39Cited by
9References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1995
Grant dateMay 7, 1996
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P1/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of Formula I EQU (NeuAc-.alpha.(2-3)-Gal-.beta.(1)-(--X--).sub.m -(--Y--).sub.n -).sub.p -Z wherein PA1 X=a chemical bond or a group capable of linking the galactose to either the linking group Y or the multivalent support Z; PA1 wherein the C.sub.1 glycosidic oxygen of galactose may be replaced by N, S or C; PA1 Y=a linking group; PA1 Z=a multivalent support; PA1 m=0 or 1; PA1 n=0 or 1; and PA1 p=an integer of 2-1,000 is described. Also described is a method for treating and/or inhibiting gastric and duodenal ulcers, comprising administering a pharmaceutical composition comprising an oligosaccharide of Formula II EQU NeuAc-.alpha.(2-3)-Gal-.beta.(1)-A wherein PA1 A=a group capable of bonding to the galactose; PA1 wherein the C.sub.1 glycosidic oxygen of galactose may be replaced by N, S or C.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.