Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US5514800A · kind A · utility
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10Claims
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Key dates
| Filing date | Sep 20, 1993 |
| Grant date | May 7, 1996 |
| Priority date | — |
| Expiry date | Sep 20, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substituted imidazolyl-alkyl-piperazine and diazepine derivatives of Formula A: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, m, n and q are defined as in the specification, and the pharmaceutically acceptable salts thereof. The compounds have calcium entry blocking activity with selectivity for cerebral blood vessels, and have protective activity against some of the deleterious effects resultant upon cerebral ischemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.