Method of preparing 1-amino-2, 6-dimethylpiperidine

US5514806A · kind A · utility

Assignee

• Cassella Aktiengesellschaft · DE

Inventors

• Wolfgang Rrbczynski · Rodenbach, DE
• Manfred Schrod · Weiterstadt, DE

Key dates

• Filing date: May 17, 1994
• Grant date: May 7, 1996
• Expiry date: May 17, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/30
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to improved processes for the preparation of 1-amino-2,6-dimethylpiperidine whereby the yield is more than 90%. The processes involve the hydrogenation of 1-nitroso-2,6-dimethylpiperidine in the presence of a palladium catalyst partly poisoned with iron ions but in the substantial absence of water or other solubilizing agents added to the reaction vessel.