Patent · US Expired

Fluidized intestinal submucosa and its use as an injectable tissue graft

US5516533A · kind A · utility

185Cited by
2References
30Claims
0Family size

Assignees

Inventors

Key dates

Filing dateNov 22, 1994
Grant dateMay 14, 1996
Priority date
Expiry dateNov 22, 2014

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61L2400/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A fluidized, injectable tissue graft composition is described. The composition comprises comminuted intestinal submucosa or protease-digested intestinal submucosa. Methods for the preparation and use of injectable tissue graft compositions are described. In preferred embodiments the tissue graft material is prepared from the intestinal submucosa comprising the tunica submucosa, the muscularis mucosa and the stratum compactum of a segment of intestinal tissue of a warm-blooded vertebrate. Effective amounts of the fluidized graft compositions can be injected to promote repair tissue defects by inducing formation of endogenous tissues.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.