Patent · US Expired

Method of determination of pivka

US5516640A · kind A · utility

42Cited by
2References
1Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 18, 1994
Grant dateMay 14, 1996
Priority date
Expiry dateApr 18, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/811
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

To provide a simple immunochemical assay of a PIVKA of every kind (PIVKA-VII, -IX, -X, -C, -S or -Z: protein induced by vitamin K absence) corresponding to a vitamin K-dependent protein. It has been confirmed that a PIVKA of every kind can be determined according to the double antibody sandwich method wherein use is made of a solid-supported anti-PIVKA-II monoclonal antibody. There is also disclosed a reagent for determination of a PIVKA of every kind according to the above-mentioned method.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.