Method of determination of pivka
US5516640A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 18, 1994 |
| Grant date | May 14, 1996 |
| Priority date | — |
| Expiry date | Apr 18, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/811
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
To provide a simple immunochemical assay of a PIVKA of every kind (PIVKA-VII, -IX, -X, -C, -S or -Z: protein induced by vitamin K absence) corresponding to a vitamin K-dependent protein. It has been confirmed that a PIVKA of every kind can be determined according to the double antibody sandwich method wherein use is made of a solid-supported anti-PIVKA-II monoclonal antibody. There is also disclosed a reagent for determination of a PIVKA of every kind according to the above-mentioned method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.