Truncated thrombomodulin, recombinant production thereof, and therapeutic agent
US5516659A · kind A · utility
13Cited by
6References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 19, 1994 |
| Grant date | May 14, 1996 |
| Priority date | — |
| Expiry date | Sep 19, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a novel polypeptide which is obtained by means of genetic recombination DNA techniques and has thrombin binding ability, anticoagulant activity and thrombolytic activity. The polypeptide of the present invention can be produced in a large quantity and efficiently by means of genetic recombination techniques. Since the polypeptide of the present invention exhibits anticoagulant activity and thrombolytic activity without generating side effects such as bleeding tendency, it can be applied effectively to the prevention and treatment of hypercoagulability-related diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.