Patent · US Expired

LHRH antagonists having lactam groups at the N-terminus

US5516759A · kind A · utility

5Cited by
3References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 8, 1994
Grant dateMay 14, 1996
Priority date
Expiry dateDec 8, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Peptides possessing LHRH antagonistic activity, and useful for the controlling the release of LHRH in mammals are decapeptide analogues of LHRH having a lactam group at the N-terminus of the formula ##STR1## where n is 1, 2, or 3 and R.sup.1 is selected from the group consisting of hydrogen, benzyl, 4-chlorobenzyl, 2-methylnaphth-1-yl, 1-methylnaphth-2-yl, and quinolin-3-ylmethyl.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.