Patent · US Expired

Chiral separations by simulated moving bed chromatography operating at low k' values

US5518625A · kind A · utility

12Cited by
5References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 13, 1995
Grant dateMay 21, 1996
Priority date
Expiry dateFeb 13, 2015

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01D15/3833
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

Resolution of a racemic mixture of organic materials by simulated moving bed chromatography using a chiral stationary phase can be routinely effected at atypically low values of k' with recoveries of at least 95% and an optical purity of at least 95%. In particular, values in the range 0.1<k'<1.0 are recommended with a resulting savings in mobile phase consumption, inventory, and recovery.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.