Tissue regeneration matrices by solid free form fabrication techniques
US5518680A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 23, 1994 |
| Grant date | May 21, 1996 |
| Priority date | — |
| Expiry date | Feb 23, 2014 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29K2995/0064
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Solid free-form techniques for making medical devices for implantation and growth of cells from polymers or polymer/inorganic composites using computer aided design are described. Examples of SFF methods include stereo-lithography (SLA), selective laser sintering (SLS), ballistic particle manufacturing (BPM), fusion deposition modeling (FDM), and three dimensional printing (3DP). The devices can incorporate inorganic particles to improve the strength of the walls forming the pores within the matrix and to provide a source of mineral for the regenerating tissue. The devices can contain tissue adhesion peptides, or can be coated with materials which reduce tissue adhesion. The macrostructure and porosity of the device can be manipulated by controlling printing parameters. Most importantly, these features can be designed and tailored using computer assisted design (CAD) for individual patients to optimize therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.