2-aminoalkyl-5-aminoalkylamino substituted-isoquinoindazole-6(2H)-ones

US5519029A · kind A · utility

Assignees

• Boehringer Mannheim Italia, S.p.A. · IT
• University of Vermont and State Agricultural College · US

Inventors

• A. Paul Krapcho · Shelburne, US
• Ernesto Menta · Parma, IT
• Ambrogio Oliva · Saronno, IT
• Silvano Spinelli · Milano, IT

Key dates

• Filing date: Aug 11, 1993
• Grant date: May 21, 1996
• Expiry date: Aug 11, 2013

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention is directed to 2-aminoalkyl-5-aminoalkylamino substituted isoquino [8,7,6-cd]indazole-6-(2H)-ones and to 2-aminoalkyl-5-aminoalkylamino substituted-isoquino [5,6,7-cd] indazole-6(2H)-ones. These compounds have been shown to have antitumor activity.