Homobidental, trifunctional linkers, method for their preparation and use in immunologically active conjugates

US5519142A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Eva Hoess · Starnberg, DE
• Erasmus Huber · Garching bei München, DE
• Christine Markert-Hahn · Penzberg, DE
• Beatus Ofenloch-Haehnle · Wielenbach, DE

Key dates

• Filing date: Mar 29, 1994
• Grant date: May 21, 1996
• Expiry date: Mar 29, 2014

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/54353
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Compound of the general formula ##STR1## wherein R is an ester-activating group, m and n are identical or different and 0-6, p=0, 2-4, and q and s=1, p=0 if s=0 and p=2-4 if s=1. The compound is novel and suitable for the reproducible coupling of immunological substances at a high yield.