Patent · US Expired

Bicyclic substituted hexahydrobenz[e]isoindole .alpha.-1 adrenergic antagonists

US5521181A · kind A · utility

7Cited by
1References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 27, 1995
Grant dateMay 28, 1996
Priority date
Expiry dateJan 27, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to a compound of the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are .alpha.-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.-1 receptors and treating BPH.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.