Patent · US Expired

NMDA-blocking pharmaceuticals

US5521215A · kind A · utility

46Cited by
4References
8Claims
0Family size

Assignees

Inventors

Key dates

Filing dateFeb 7, 1994
Grant dateMay 28, 1996
Priority date
Expiry dateFeb 7, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/80
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Pharmaceutical compositions are described for preventing neurotoxicity, crising as active ingredient the stereospecific (+) enantiomer, having (3S,4S) configuration of .DELTA..sup.6 tetrahydrocannabinol type compounds. The compositions are particularly effective in alleviating and even preventing neurotoxicity due to acute injuries to the central nervous system, including mechanical trauma, compromised or reduced blood supply as may occur in cardiac arrest or stroke, or poisonings. They are also effective in the treatment of certain chronic degenerative diseases characterized by gradual neuronal loss.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.