Transgenic swine compositions and methods
US5523226A · kind A · utility
107Cited by
3References
5Claims
0Family size
Assignees
Inventor
Key dates
| Filing date | May 14, 1993 |
| Grant date | Jun 4, 1996 |
| Priority date | — |
| Expiry date | May 14, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Transgenic swine, and compositions and methods for making and using same, are provided. Central to the invention are porcine (Sus scrofa) embryonic stem cell lines and methods for establishing them. Cells of such lines are transformed with exogenous genetic material of interest and then used to provide chimeric swine, which have germ cells comprising the exogenous genetic material. The chimeric swine are bred to provide transgenic swine. Transgenic swine of the invention can be used to provide human proteins or peptide hormones or can be used as xenograft donors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.