Detection and therapy of lesions with biotin/avidin conjugates
US5525338A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Aug 21, 1992 |
| Grant date | Jun 11, 1996 |
| Priority date | — |
| Expiry date | Aug 21, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are provided for detecting and/or treating lesions in a patient. The methods use a targeting composition comprised of a biotin and targeting protein conjugate or an avidin and targeting protein conjugate; optionally, a clearing composition comprised of avidin, when the targeting composition is a biotin conjugate, or biotin, when the targeting composition is a avidin conjugate; a detection or therapeutic composition comprised of a conjugate of avidin or biotin with a targeting protein and detection or therapeutic agent; and, optionally, another detection or therapeutic composition comprised of avidin or biotin conjugated to a detection or therapeutic agent. Compositions and kits useful in the methods are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.