42-Epi-rapamycin and pharmaceutical compositions thereof
US5525610A · kind A · utility
78Cited by
34References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 26, 1995 |
| Grant date | Jun 11, 1996 |
| Priority date | — |
| Expiry date | Apr 26, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention comprises the compound of 42-Epimer Rapamycin of the following structural formula: ##STR1## as well as pharmaceutical compositions containing 42-Epi-Rapamycin and its use in methods for inducing immunosuppression and methods for treating transplantation rejection, graft vs. host disease, autoimmune diseases, diseases of inflammation, solid tumors, fungal infections, adult T-cell leukemia/lymphomas and hyperproliferative vascular disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.