Active ingredient patch for low-melting and/or volatile active ingredients

US5527536A · kind A · utility

Assignee

• Schwarz Pharma Ltd. · DE

Inventors

• Hans P. Merkle · Zürich, CH
• Klaus Nagels · Bonn, DE
• Dietrich Schacht · Recklinghausen, DE
• Hans-Michael Wolff · Monheim, DE

Key dates

• Filing date: Feb 27, 1995
• Grant date: Jun 18, 1996
• Expiry date: Feb 27, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L15/58
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns a patch for the controlled release of readily available volatile active substances to the skin, the patch comprising a back layer and, bonded to it, a water-insoluble adhesive film consisting of a pressure-sensitive fusion adhesive, plus a detachable film covering the adhesive film. The patch is characterized in that the pressure-sensitive fusion adhesive contains a triple-block copolymer of polystyrene block copoly(ethylene/butylene) block polystyrene (SEBS) at a concentration of 10 to 80% by wt., and an active substance which, at the temperature at which the adhesive bonds, is a readily volatile liquid, and which is present at a concentration of 2.5 to 25% by wt.