Tablets with thioctic acid of specific particle size

US5527539A · kind A · utility

Assignee

• Asta Medica Aktiengesellschaft · DE

Inventors

• Werner Sarlikiotis · Bielefeld, DE
• Helmut Hettche · Dietzenbach, DE

Key dates

• Filing date: Jan 5, 1995
• Grant date: Jun 18, 1996
• Expiry date: Jan 5, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/2095
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a drug formulation in the form of tablets containing thioctic acid (.alpha.-lipoic acid) with an active ingredient content between 45% by weight and 99.9% by weight. The invention is characterized in that 20% to 100% of the active ingredient used has a particle size exceeding 100 .mu.m, particulary between 100 .mu.m and 710 .mu.m, preferably 30% to 80% a particle size between 200 .mu.m and 710 .mu.m.