Patent · US Expired

HIV protease inhibitors useful for the treatment of AIDS

US5527799A · kind A · utility

7Cited by
2References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 21, 1995
Grant dateJun 18, 1996
Priority date
Expiry dateMar 21, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2602/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of formula ##STR1## where R.sup.1 and R.sup.2 are independently hydrogen or optionally-substituted C.sub.1-4 alkyl or aryl, or R.sup.1 and R.sup.2 are joined together to form a monocyclic or bicyclic ring system, are HIV protease inhibitors. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.