Process for preparing enantiomerically pure diarylprolinols

US5527923A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Franz D. Klingler · Griesheim, DE
• Rainer Sobotta · Ingelheim am Rhein, DE

Key dates

• Filing date: May 4, 1995
• Grant date: Jun 18, 1996
• Expiry date: May 4, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D207/16
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a new process for preparing enantiomerically pure diarylprolinols, especially (R)-(+)- or (S)-(-)-2-(diphenylhydroxymethyl)-pyrrolidine (R)-(+)- or (S)-(-)-.alpha.,.alpha.-diphenyl-(2-pyrrolidinyl)-methanol) starting from proline.