Cyclohexadiene derivatives

US5530014A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Klaus Urbahns · Kasai, JP
• Hans-Georg Heine · Krefeld, DE
• Bodo Junge · Wuppertal, DE
• Rudolf Schohe-Loop · Wuppertal, DE
• Hartmund Wollweber · Wuppertal, DE
• Henning Sommermeyer · Neunburg vorm Wald, DE
• Thomas Glaser · Overath, DE
• Reilinde Wittka · Neunburg vorm Wald, DE
• Jean De Vry · Stolberg, DE

Key dates

• Filing date: Aug 18, 1995
• Grant date: Jun 25, 1996
• Expiry date: Aug 18, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The cyclohexadiene derivatives are prepared by reaction of cyclohexanones with amines and subsequent dehydration. The compounds are suitable as active compounds in medicaments on account of their property of being selective modulators of calcium channel-dependent potassium channels.