Replicative RNA-based amplification/detection systems
US5532126A · kind A · utility
5Cited by
3References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 27, 1993 |
| Grant date | Jul 2, 1996 |
| Priority date | — |
| Expiry date | Sep 27, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/701
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to the use of functional reporter molecules in the detection and measurement of nucleic acid sequences in a sample, as a determination, for example, of pathogenic disease existence or potential. The invention is predicated on the utilization of a transcription step between the production of an appropriate reporter molecule and replication based amplification in order to increase the number of detectable species as an indirect reference to target nucleic acid sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.