Mutated alpha virus
US5532154A · kind A · utility
37Cited by
0References
12Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 21, 1994 |
| Grant date | Jul 2, 1996 |
| Priority date | — |
| Expiry date | Mar 21, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/36122
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a composition of matter, comprising a non-infectious, mutated virus suitable for use in preparing a vaccine. A plasmid adapted for expression in a recombinant cell comprising DNA encoding non-infectious mutated virus protein and regulatory elements necessary for expression of said DNA in the cell. Also provided are methods of inhibiting the spread of infection of a virus comprising the step of contacting said virus with a compound that inhibits thiol-reductase/protein disulfide isomerase activity in said virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.