Vivo dosimeter for photodynamic therapy
US5533508A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 27, 1994 |
| Grant date | Jul 9, 1996 |
| Priority date | — |
| Expiry date | Jan 27, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2017/00057
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A device for measuring the fluorescence generated by photoactivated molecules during photodynamic therapy (PDT) and a method of using the device for dosimetry. The device, which comprises an isotropic spherical probe and detector electronics, simultaneously measures the space irradiance and time-integrated fluorescence during PDT. It is shown that there is a correlation between the time-integrated fluorescence generated during PDT treatment of a tumor and the delay in the regrowth of the tumor. The device provides the simultaneous measurement of the space irradiance and integrated fluorescence which measurements enable real time dosimetry during PDT.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.