N-acyl-2,3-benzodiazepine derivatives pharmaceutical compositions containing them and process for preparing same
US5536832A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 17, 1995 |
| Grant date | Jul 16, 1996 |
| Priority date | — |
| Expiry date | Apr 17, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to novel N-acyl-2,3-benzodiezapine derivatives of the general formula (I), their stereoisomers and acid-addition salts, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I) PA0 R stands for a C.sub.1-6 alkanoyl group optionally substituted by a methoxy, cyano, carboxyl, amino, C.sub.1-4 alkylamino, di(C.sub.1-4 alkyl)amino, pyrrolidino, phthalimido or phenyl group, or by one or more halogen(s); or R is a benzoyl, cyclopropanecarbonyl, C.sub.1-5 alkylcarbamoyl or phenylcarbamoyl group; or R is absent when a double bond exists between the N(3) and C(4) atoms; PA0 R.sup.1 means hydrogen; or R.sup.1 is absent when a double bond exists between the N(3) and C(4) atoms; PA0 R.sup.2 means a C.sub.1-3 alkyl group; or PA0 R.sup.1 and R.sup.2 together stand for a methylene group and no double bond is present between the N(3) and C(4) atoms; PA0 R.sup.3 means hydrogen or a C.sub.1-4 alkanoyl group; PA0 R.sup.4 represents hydrogen; a C.sub.1-6 alkanoyl group optionally substituted by a methoxy, cyano, carboxyl, amino, C.sub.1-4 alkylamino, di(C.sub.1-4 alkyl)amino, pyrrolidino, phthalimido or phenyl group or by one or …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.