Process for enzymatic production of isomerically pure isosorbide-2 and 5-monoesters and their conversion to isosorbide-2 and -5 nitrate
US5538891A · kind A · utility
15Cited by
1References
27Claims
0Family size
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Key dates
| Filing date | Feb 4, 1994 |
| Grant date | Jul 23, 1996 |
| Priority date | — |
| Expiry date | Feb 4, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/931
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for the enzymatic production of isomerically pure compounds having the general formulae I and II ##STR1## in which the substituents R have the meanings stated in the claims, as well as their use for the production of isomerically pure isosorbide-2-nitrate having the formula V and isosorbide-5-nitrate having the formula VI, ##STR2## which are both important as therapeutic agents for coronary diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.