2,4-diamino-3-hydroxycarboxylic acid derivatives

US5538997A · kind A · utility

Assignee

• Sandoz AG · CH

Inventors

• Andreas Billich · Wien, AT
• Brigitte Charpiot · Nice, FR
• Peter Ettmayer · Wien, AT
• Hubert Gstach · Wien, AT
• Philipp Lehr · Spittal an der Drau, AT
• Dieter Scholz · Wien, AT

Key dates

• Filing date: Jan 3, 1994
• Grant date: Jul 23, 1996
• Expiry date: Jan 3, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of formula I ##STR1## wherein the substituents have various significances. They can be prepared by conventional methods, e.g. coupling, substitution, deprotection or protection reactions. They possess interesting pharmacological properties and are thus indicated for use in the treatment of retroviral infections, particularly as HIV proteinase inhibitors.