Process for the preparation of N-alkanoyl-polyhydroxyalkylamines

US5539134A · kind A · utility

Assignee

• BASF SE

Inventors

• Beate Strecker · Ludwigshafen, DE
• Helmut Wolf · Holzkirchen, DE
• Gerhard Wolf · Mannheim, DE
• Alfred Oftring · Bad Dürkheim, DE
• Hans-Heinrich Bechtolsheimer · Dittelsheim-Heßloch, DE
• Dieter Hertel · Leimen, DE

Key dates

• Filing date: Apr 24, 1995
• Grant date: Jul 23, 1996
• Expiry date: Apr 24, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C231/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The preparation von N-alkanoyl-polyhydroxyalkylamines I in which ##STR1## in which Z stands for the polyhydroxyalkyl radical of a monosaccharide or oligosaccharide, PA1 R.sup.1 denotes hydrogen or C.sub.1 -C.sub.8 alkyl and PA1 R.sup.2 denotes C.sub.1 -C.sub.21 alkyl, by the reaction of polyhydroxyalkylamines of the general formula II EQU Z--NH--R.sup.1 (II), with alkyl carboxylates of the general formula III ##STR2## in which R.sup.3 denotes a C.sub.1 -C.sub.4 alkyl radical, in the presence of a basic catalyst, in which PA1 (a) all of the ester III is placed in the reactor and is heated to the reaction temperature, and the amine II is metered in in the form of a melt while the reaction proceeds, while alcohol R.sup.3 --OH formed is continuously removed by distillation, PA1 (b) the reaction is carried out at a temperature of from 55.degree. to 110.degree. C., and PA1 (c) the reaction is carried out in the absence of organic solvents.