Carbohydrate-based vaccine and diagnostic reagent for trichinosis
US5541075A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 5, 1993 |
| Grant date | Jul 30, 1996 |
| Priority date | — |
| Expiry date | Feb 5, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5308
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to Trichinella vaccines that include at least one tyvelose-containing oligosaccharide or functional equivalent thereof, to Trichinella vaccines that include at least one fucose-containing oligosaccharide or functional equivalent thereof, and to the use of such vaccines to protect animals from Trichinella infections, and particularly from trichinosis caused by Trichinella spiralis infection. Such vaccines can also be used to produce antibodies that are capable of protecting an animal from Trichinella infections and of diagnosing such infections. The present invention also relates to Trichinella diagnostic reagents that include at least one tyvelose-containing oligosaccharide, or functional equivalent thereof, and use of such reagents to detect Trichinella, and particularly Trichinella spiralis infections. The present invention also includes diagnostic kits based on such reagents and anti-Trichinella-spiralis drugs based on the knowledge that tyvelose is produced by Trichinella spiralis parasites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.