Glyoxylic acid/aminomethylphosphonic acid mixtures prepared using a microbial transformant
US5541094A · kind A · utility
10Cited by
14References
5Claims
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Key dates
| Filing date | Jun 3, 1994 |
| Grant date | Jul 30, 1996 |
| Priority date | — |
| Expiry date | Jun 3, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/40
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An improved enzymatic process for reacting glycolic acid and oxygen in an aqueous solution in the presence of aminomethylphosphonic acid wherein the improvement comprises using a microbial cell catalyst that expresses glycolate oxidase (e.g., Pichia pastoris, Hansenula polymorpha, Aspergillus nidulans, or Escherichia coli) and endogenous catalase; soluble catalase may also be included. The resulting mixtures are useful intermediates in the production of N-(phosphonomethyl)glycine.
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