Patent · US Expired

6-heterocycyclyl pyrazolo[3,4-d]pyrimidin-4-ones and compositions and method of use thereof

US5541187A · kind A · utility

34Cited by

7References

29Claims

0Family size

Assignee

Sterling Winthrop Inc. · US

Inventors

Edward R. Bacon · East Greenbush, US
Baldev Singh · East Greenbush, US
George Y. Lesher · Rockville Centre, US

Key dates

Filing date	Nov 30, 1993
Grant date	Jul 30, 1996
Priority date	—
Expiry date	Nov 30, 2013

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Novel 6-heterocyclyl-pyrazolo[3,4-d]pyrimidin-4-ones, useful in treating cardiovascular disease, are prepared by reacting a 5-amino-1H-pyrazole-4-carboxamide with heterocyclyl-carboxaldehyde or by reacting a 5-amino-1H-pyrazole-4-carbonitrile with a heterocyclylcarboxamidine, followed by diazotization and hydrolysis of the resulting 4-amino-6-heterocyclyl-pyrazolo[3,4-d]pyrimidine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.