Administration of atipamezole to elicit a yohimbine-like alpha-adrenoreceptor antagonistic noradrenergic transmission
US5541211A · kind A · utility
7Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 16, 1995 |
| Grant date | Jul 30, 1996 |
| Priority date | — |
| Expiry date | Mar 16, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/415
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is in the art of eliciting a yohimbine-like alpha-adrenoreceptor antagonistic noradrenergic neurotransmission male sexual activity response in penile erection. The improvement involves a more rapid onset of action and improved effect than that of yohimbine, consisting essentially of the step of administering the compound atipamezole or a pharmaceutically acceptable acid addition salt thereof to a male in need thereof. Atipamezole or pharmaceutically acceptable acid salt thereof may be administered perorally, intravenously, intramuscularly, transmucosally or transdermally.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.