1-Alkoxy-2-(alkoxy- or cycloalkoxy-)-4-(cyclothioalkyl- or cyclothioalkenyl-) benzenes as inhibitors of cyclic AMP phosphodiesterase and tumor necrosis factor
US5541219A · kind A · utility
8Cited by
11References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 3, 1994 |
| Grant date | Jul 30, 1996 |
| Priority date | — |
| Expiry date | Nov 3, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D335/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to 1-alkoxy-2-(alkoxy- or cycloalkyloxy-)-4-(cyclothioalkyl- or cyclothioalkenyl-)benzene compounds that inhibit cyclic AMP phosphodiesterase or tumor necrosis factor (TNF) and are useful in treating patients suffering from disease state capable of being modulated by inhibiting production of cyclic AMP phosphodiesterase or TNF by administering the compound to the patient. The invention is also directed to the preparation of these compounds, pharmaceutical compositions containing these compounds and methods for their pharmaceutical use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.