Chloropyridinium chlorides and process for their preparation

US5541332A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Reinhard Lantzsch · Leverkusen, DE
• Klaus Jelich · Wuppertal, DE
• Carl Casser · Neunburg vorm Wald, DE
• Christoph Mannheims · Leverkusen, DE
• Knud Lawrenz · Neunburg vorm Wald, DE

Key dates

• Filing date: Jan 4, 1995
• Grant date: Jul 30, 1996
• Expiry date: Jan 4, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/61
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of a chloropyridine of the formula ##STR1## which comprises reacting an enamide of the formula ##STR2## with a chlorinating agent in the presence of a di-substituted formamide ##STR3## in which R.sup.4 and R.sup.5 each individually is alkyl or cycloalkyl or together are alkanediyl, at a temperature between about -30.degree. C. and 100.degree. C., thereby to produce a compound of the formula ##STR4## and subjecting said compound to thermal cleavage. Compounds I are novel. Compounds IV are known intermediates for agrochemicals and pharmaceuticals.