Pharmaceutical composition and method for the suppression of factor VIII inhibitor production
US5543145A · kind A · utility
2Cited by
8References
26Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 21, 1994 |
| Grant date | Aug 6, 1996 |
| Priority date | — |
| Expiry date | Jul 21, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition suitable for administration to human beings for suppressing the production of factor VIII inhibitor includes: PA1 an immune complex of factor VIII antigen component and factor VIII inhibitor component, the components being present in a ratio such that the inhibitor blocks essentially all relevant binding sites of the antigen; and PA1 a pharmacologically acceptable carrier or diluent. The invention also provides a method of administering the compositions to suppress the production of inhibitor to factor VIII.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.