Patent · US Expired

Process for the preparation of 5-fluoroanthranilic alkyl esters and/or 5-fluoroanthranilic acid

US5543550A · kind A · utility

1Cited by

2References

37Claims

0Family size

Assignee

Hoechst GmbH · DE

Inventors

Jochen Rapp · Frankfurt, DE
Siegfried Planker · Bocholt, DE
Theodor Papenfuhs · Frankfurt, DE
G unter Bartels · Burgwedel, DE

Key dates

Filing date	Oct 6, 1994
Grant date	Aug 6, 1996
Priority date	—
Expiry date	Oct 6, 2014

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C227/06
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a process for the preparation of 5-fluoroanthranilic alkyl esters and/or 5-fluoroanthranilic acid, which comprises dissolving a 3-fluorobenzoic alkyl ester in sulfuric acid and reacting the solution with a nitrating acid at from -10.degree. to 30.degree. C., then adding water, separating off the nitrated reaction product and reacting it with hydrogen at from 50.degree. to 120.degree. C. under elevated pressure in the presence of a catalyst comprising a metal of the platinum group and sulfur, and, if desired, removing 5-fluoroanthranilic alkyl esters by distillation and hydrolyzing them to give 5-fluoroanthranilic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.