Patent · US Expired

Method for treating a mammal suffering from a T-cell medicated disorder with a CHO-Glycosylated antibody

US5545404A · kind A · utility

64Cited by
2References
7Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 3, 1994
Grant dateAug 13, 1996
Priority date
Expiry dateNov 3, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/41
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to a CHO cell-line capable of producing antibody, the cell-line having been co-transfected with a vector capable of expressing the light chain of the antibody and a vector capable of expressing the heavy chain of the antibody wherein the vectors contain independently selectable markers; also included is a CHO cell-line capable of producing a human antibody or an altered antibody, the cell-line having been transfected with a vector capable of expressing the light chain of the antibody and the heavy chain of the antibody; process for the production of antibody using a CHO cell-line and antibody having CHO glycosylation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.