Patent · US Expired

N-[1, (1-1)-dialkyloxy]-and N-[1, (1-1)-dialkenyloxy]-alk-1-yl-n,n,n-tetrasubstituted ammonium lipids and uses therefor

US5545412A · kind A · utility

108Cited by
43References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 3, 1995
Grant dateAug 13, 1996
Priority date
Expiry dateApr 3, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/829
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R.sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, aralkyl of 7 to 11 carbon atoms, or when two or three of R.sup.3, R.sup.4, and R.sup.5 are taken together to form quinuclidino, piperidino, pyrrolidino, or morpholino, n is 1 to 8; and X is a pharmaceutically acceptable anion.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.