Antemortem diagnostic test for alzheimer's disease
US5545566A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 5, 1995 |
| Grant date | Aug 13, 1996 |
| Priority date | — |
| Expiry date | Jun 5, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/92
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An antemortem diagnostic test for neurodegenerative disease, particularly Alzheimer's disease, involves the collection of a sample of bodily fluid; the analysis of the concentration of neuronal membrane phospholipids and phospholipid metabolites, or the ratio of a phospholipid to its metabolite, in the sample; and the correlation of the concentration or the ratio to the corresponding value from control samples. The method can be used to determine the presence or the possibility that an individual can develop a neurodegenerative disease, such as Alzheimer's disease; to follow the course of neurodegenerative disease in an individual; and to validate the efficacy of a drug used to treat a neurodegenerative disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.